| A Place for Meow Rescue | Rapid City | B | $125K |
| Aberdeen Area Humane Society | Aberdeen | F | $1.50M |
| Allcatsrescue | Sioux Falls | C | $107K |
| Almost Home Canine Rescue | Sioux Falls | C | $247K |
| Battle Mountain Humane Society | Hermosa | C | $663K |
| Beadle County Humane Society | Huron | C | $274K |
| Black Hills Mountain Lion Foundation | Piedmont | A | $26K |
| Black Hills Raptor Center | Caputa | D | $257K |
| Border Paws Dog Rescue | Rapid City | C | $61K |
| Brookings Regional Humane Society Inc | Brookings | B | $364K |
| Cats Meow Foster Care Inc | Mitchell | F | $44K |
| Codington County Pro Pheasants Inc | Watertown | B | $34K |
| Dakota Dachshund Rescue Inc | Sioux Falls | C | $227K |
| Friends of the Twin City | Lead | F | $65K |
| Gentle Spirit Horses Rescue & Sanctuary | Scotland | F | $129K |
| Glacial Lakes Humane Society and Shelter | Watertown | D | $358K |
| Happy Tails Haven | Piedmont | D | $120K |
| Heartland Humane Society Inc | Yankton | C | $435K |
| Humane Society of the Black Hills | Rapid City | C | $3.29M |
| Institute of the Range & the American Mu | Hot Springs | C | $2.53M |
| Lake Area Zoological Society | Watertown | D | $463K |
| Lake Traverse Animal Rezcue | Sisseton | B | $166K |
| Milbank Animal Rescue Services | Milbank | C | $64K |
| Mitchell Rodeo Foundation Inc | Mitchell | D | $254K |
| Oglala Pet Project | Kyle | C | $50K |
| Operation Pets Inc | Rapid City | B | $69K |
| Pierre-Fort Pierre Area Humane Society | Pierre | C | $218K |
| Save Them All Rescue Services | Hot Springs | F | $80K |
| SD Caring for Canines | Rapid City | C | $78K |
| Shiloh Charitable Trust | Newell | D | $145K |
| Sioux Empire Pit Bull Rescue Inc | Sioux Falls | D | $274K |
| Sioux Empire TNR Coalition | Sioux Falls | D | $143K |
| Sioux Falls Area Humane Society | Sioux Falls | D | $2.35M |
| Sioux Falls Zoo & Aquarium | Sioux Falls | C | $16.10M |
| South Dakota Discovery Center | Pierre | C | $851K |
| South Dakota Walleyes Unlimited Inc | Rapid City | B | $39K |
| South Dakota West River Spay-Neutercoalition | Deadwood | C | $134K |
| South Dakota Wildlife Federation | Pierre | B | $115K |
| Spirit of the Hills Wildlife Sanctuary | Spearfish | F | $26K |
| Tanka Fund | Kyle | C | $1.12M |
| Wbfi Research Foundation | Britton | C | $32K |
| Webster Paws Walk | Webster | C | $7,479 |
Charity Clarity