| Advanced Technology International | Summerville | B | $4.87B |
| American Chemical Society | Aiken | F | $71K |
| Archaeological Institute of the Pee Dee | Florence | C | $58K |
| CDC Education Foundation | Charleston | C | $65K |
| Foundation for Southeastern | Aiken | B | $0 |
| Innovision Awards Organization | Greenville | B | $77K |
| International Mechanical Diagnosis | Blythewood | D | $23K |
| Lowcountry STEM Collaborative | Charleston | F | $0 |
| National Council of Examiners for Engineering and Surveying | Greenville | B | $45.70M |
| National Science and Engineering | Lake City | C | $98K |
| Ncees Foundation | Greenville | D | $3.15M |
| One Nation Innovation | Columbia | C | $12.98M |
| Palmetto Innovasphere Inc | Piedmont | C | $384K |
| SC Division of the International | Charleston | A | $17K |
| SC Thrive | Columbia | A | $7.97M |
| Scbio Foundation | Greenville | D | $0 |
| South Carolina Entomological Society | Columbia | F | $17K |
| South Carolina Research Authority | Columbia | C | $16.23M |
| South Carolina Society of Nuclear | West Columbia | C | $19K |
| South Coast Cyber Center Inc | Beaufort | C | $83K |
| The Charleston Center for | Charleston | C | $221K |
| University Industry Demonstration | Columbia | B | $4.25M |
| VC Expeditions | Charleston | C | $85K |
Charity Clarity