| A Steady Hand Foundation Inc | Summerville | C | $164K |
| Abby's Friends Inc | Charleston | F | $0 |
| Abvi Foundation | Charleston | D | $494K |
| Advanced Institute for Development and Learning | Greenville | C | $858K |
| Affinity Health Center | Rock Hill | A | $27.75M |
| Akanimo Cancer Foundation | Greer | B | $40K |
| All 4 Autism | Florence | B | $110K |
| Annual SC Hiv-Std Conference Inc | Columbia | C | $101K |
| Aura Cares Inc | Summerville | B | $1,300 |
| Battle Buddies | Piedmont | C | $180K |
| Be the Change Charleston Inc | Charleston | A | $73K |
| Beautiful Gate Center | N Charleston | C | $1.12M |
| Beginnings for Parents of Children | West Columbia | C | $418K |
| Bella Muntean-Angel Heart of Hope | Greer | C | $34K |
| Broken Wing Farm | Honea Path | F | $0 |
| Calhoun Traumatic Brain Injury Foundation | Columbia | C | $186K |
| Cancer Association of Anderson | Anderson | F | $914K |
| Cancer of Many Colors | Lexington | C | $208K |
| Canhope | Aiken | B | $72K |
| Caring Fore Coby | Summerville | D | $22K |
| Carolina Children's Charity Inc | Charleston | B | $227K |
| Cces Endowment Corporation | Greenville | C | $742K |
| Champion Autism Network | Surfside BCH | F | $161K |
| Chrysalis Autism Center Inc | Rock Hill | A | $1.12M |
| Columbia Parkinsons Support Group | Columbia | C | $5,150 |
| Committe on Better Racial Assurance | N Charleston | C | $198K |
| Commonwealth Cares Foundation | Daniel Island | C | $10K |
| Cystic Fibrosis Bites | MT Pleasant | B | $33K |
| Diann Shaddox Foundation | Aiken | B | $62K |
| Dragon Boat Charleston | Charleston | B | $235K |
| Duke Arthroplasty Society Inc | Irmo | C | $190K |
| Federation Center of the Blind | Columbia | C | $284K |
| Federation of the Blind of SC | Columbia | C | $284K |
| Fighting to Win Inc | Beech Island | C | $168K |
| For the Win Inc | Bluffton | A | $7,102 |
| Friends of Ithemba | Ninety Six | C | $46K |
| Friends of the York County Library | Rock Hill | B | $133K |
| Georgetown County Diabetes Core Gro | Georgetown | B | $23K |
| Gi Nutrition Foundation | MT Pleasant | C | $174K |
| Golden Corner Respite Care Program | Seneca | C | $22K |
| Grand Strand Down Syndrome Society | Myrtle Beach | C | $57K |
| Guardian Research Network Inc | Spartanburg | D | $8.21M |
| Hannah's Hope Ministries Inc | Roebuck | F | $2,385 |
| Happy Wheels Inc | Lexington | C | $128K |
| Head & Neck Cancer Alliance Inc | Charleston | C | $1.46M |
| Helping Others Progress Through Education Inc | Rock Hill | D | $76K |
| Hemangioma Treatment Foundation Inc | Charleston | F | $0 |
| Hoops Fight Als | Columbia | F | $35K |
| James R Clark Memorial Sickle Cell | Columbia | C | $1.33M |
| Jeremiah Henry Kendrick Memorial Foundation | Goose Creek | D | $2,567 |
| Jesses Wish | Bluffton | F | $12K |
| Joyful Journeys Inc | Bluffton | B | $666K |
| Latin America Leukemia Net Lalnet | North Augusta | D | $217 |
| Lions Vision Services | Columbia | C | $1.38M |
| Louvenia D Barksdale Sickle Cell Anemia Foundatio | Spartanburg | C | $299K |
| Lowcountry Autism Foundation Inc | Bluffton | C | $357K |
| Lowcountry Ovarian Cancer Alliance | Daniel Island | C | $50K |
| Mod Dental Aesthetics | Charleston | C | $8,000 |
| National Federation of the Blind of SC | Columbia | C | $1.76M |
| Neuroendocrine Cancer Awareness Network | Fort Mill | C | $405K |
| North Charleston Dental Outreach Inc | N Charleston | C | $619K |
| Nothing Pink Inc | Fort Mill | B | $575K |
| Operation Sight | MT Pleasant | C | $124K |
| Orangeburg Area Sickle Cell Anemia | Orangeburg | C | $108K |
| Ovarian Cancer Coalition of Central South Carolina | West Columbia | B | $15K |
| Partnership for Proactive Health Inc | Kiawah Island | D | $63K |
| Pickles People Inc | Charleston | C | $73K |
| Piedmont Speech and Hearing Consort | Greenville | B | $13K |
| Pledge the Pink Foundation | Bluffton | B | $1.09M |
| Rock the Block Inc | Charleston | F | $168K |
| Salem Lions Charities Inc | Salem | B | $53K |
| Servants for Sight | Greenville | C | $353K |
| Share a Smile People Helping People | Columbia | D | $700 |
| Sickle Cell Lights of Hope | Belton | C | $5,625 |
| Sma-Pme Research | Myrtle Beach | B | $70K |
| South Carolina Autism Society Inc | West Columbia | C | $1.57M |
| South Carolina Diabetes Association | Heath Springs | C | $44K |
| South Carolina Neurological Association | Columbia | C | $135K |
| South Carolina Ovarian Cancer Foundation | Greenville | C | $92K |
| South Carolina Rheumatism Society | Summerville | C | $169K |
| Support Breath of Life Inc | MT Pleasant | D | $0 |
| Team Sammie Breast Cancer Foundation in | Simpsonville | F | $259K |
| The Ark of SC | Summerville | C | $739K |
| The B Strong Group | Columbia | D | $92K |
| Tracheo-Broncho-Malacia Foundation | Chapin | C | $80K |
| Trailhead Community Farm School | Travelers RST | F | $148K |
| Walk for Autism-Charleston | N Charleston | B | $93K |
| Zions Care | Bennettsville | D | $65K |
Charity Clarity