| 1 of US | Raleigh | B | $352K |
| 24 Foundation Inc | Charlotte | D | $2.52M |
| 335 Heart Foundation Inc | Catawba | C | $5,192 |
| Abby's Army | Raleigh | C | $63K |
| Abc of NC Foundation | Winston Salem | D | $501K |
| Aces for Autism | Greenville | C | $8.69M |
| Adap Advocacy Association | Nags Head | B | $580K |
| Advocacy & Awareness for Immune Disorders | Charlotte | B | $78K |
| Advocacy House Services Inc | Greensboro | C | $70K |
| AIDS Leadership Foothills Area | Hickory | B | $1.89M |
| Aislinns Wish Foundation | Harrisburg | D | $74K |
| Amani Childrens Foundation | Winston Salem | C | $434K |
| American Board of Pediatrics Inc | Chapel Hill | C | $49.39M |
| American College of Diabetology | Fayetteville | C | $1.64M |
| American Lung Cancer Screening | Cary | C | $495K |
| Artery of Life Foundation | Raleigh | D | $25K |
| Association of Cameroon Physicians in the Americas | Waxhaw | B | $103K |
| Association of Women in Rheumatology | Fayetteville | C | $4.86M |
| Autism Charlotte | Charlotte | A | $427K |
| Autism Foundation of North | Raleigh | F | $2.61M |
| Autism Services of Mecklenburg Coun | Charlotte | A | $5.54M |
| Autismazing Corporation | New Bern | C | $6,276 |
| Autoimmune Encephalitis Alliance Inc | Durham | C | $151K |
| Back to You Foundation LTD | Raleigh | A | $0 |
| Be the Rainbow Foundation | Apex | D | $150K |
| Beauty in Giving Foundation | Greensboro | D | $21K |
| Beginnings for Parents of Children | Raleigh | D | $1.78M |
| Belovednc Inc | Raleigh | D | $7,860 |
| Bluewest Opportunities Inc | Asheville | A | $11.84M |
| Bosom Buddies Benefit Organization | Weddington | D | $161K |
| Breast Cancer Hub Corporation | Concord | C | $104K |
| Camoallistrong | Kings MTN | F | $24K |
| Camp Care Inc | Charlotte | C | $174K |
| Cancer Services Inc | Winston Salem | C | $1.78M |
| Cancer Services of Gaston Cty Inc | Gastonia | A | $493K |
| Cancer Support Community Eastern NC Inc | Greenville | B | $101K |
| Candor NC | Durham | C | $326K |
| Carolina Breast Friends Inc | Charlotte | B | $772K |
| Carolinas Care Partnership | Charlotte | B | $4.85M |
| Ceo Roundtable on Cancer Inc | Morrisville | C | $1.28M |
| CG Foundation Inc | Morehead City | C | $51K |
| Charlotte Neuroscience Foundation | Charlotte | B | $5.38M |
| Chemocars Inc | Cornelius | D | $126K |
| Cleveland-Rutherford Kidney Association | Shelby | D | $91K |
| Coastal Bringing Up Down Syndrome of Southeastern | Wilmington | C | $124K |
| Communication Services for the Deaf and | Greensboro | A | $1.33M |
| Costello Syndrome Family Network | Black MTN | F | −$6,798 |
| Crystal Coast Autism Center | Morehead City | C | $32K |
| Cure Ahc Inc | Rolesville | D | $145K |
| David Moore Foundation | Charlotte | D | $293K |
| Dementia Alliance of North Carolina Inc | Raleigh | B | $1.30M |
| Destination Hope NC | Winston Salem | D | $1.47M |
| Diabetes Family Connection | Raleigh | B | $1.15M |
| Diabetessisters Inc | Raleigh | C | $675K |
| Don't Ever Give Up Inc | Cary | C | $24.61M |
| Down Syndrome Network of Greater Greensboro | Greensboro | C | $36K |
| Dudley's Place Inc | Huntersville | C | $1.06M |
| Dup 15Q Alliance | Matthews | D | $7.03M |
| Dusty Joy Foundation | High Point | C | $1.38M |
| Epilepsy Alliance North Carolina | Winston Salem | D | $531K |
| Epilepsy Reach Foundation | Charlotte | F | $54K |
| Face the Future Foundation Inc | Chapel Hill | D | $1,802 |
| Faith for Hayden Inc | Huntersville | D | $271K |
| Fight the Flame | Marvin | C | $52K |
| Fishin for a Cure | Emerald Isle | C | $266K |
| Gha Autism Supports | Albemarle | A | $17.06M |
| Global Vaccines Inc | Chapel Hill | D | $54K |
| Go Jen Go Foundation Inc | Charlotte | C | $532K |
| Graystone Eye Missions Inc | Hickory | A | $1,150 |
| Greensboro Cerebral Palsy | Greensboro | C | $667K |
| Guide Posts of Strength Inc | High Point | B | $177K |
| Harborpath Inc | Charlotte | C | $10.92M |
| Hatteras Island Cancer Foundation | Hatteras | D | $111K |
| Healing Pines Respite Inc | Chapel Hill | B | $68K |
| Heart Initiative Inc | Chapel Hill | C | $22K |
| Heartbright Foundation Inc | Charlotte | C | $1.30M |
| Helene Foundation | Raleigh | D | $502K |
| Hepatitis C Clinical Education Group | Raleigh | C | $171K |
| Hirsch Wellness Network Inc | Greensboro | B | $313K |
| Hive Foundation Inc | Cornelius | C | $184K |
| Honorbridge | Greenville | A | $66.15M |
| Hope at the Lake Foundation | Mooresville | B | $243K |
| Hope for Hemiplegia Inc | Siler City | B | $201K |
| Ican House Services Inc | Winston Salem | D | $279K |
| Insightful Visionaries Inc | Raleigh | D | $40K |
| Integrate Health Inc | Raleigh | C | $9.07M |
| International Sepsis Forum Inc | Murphy | C | $102K |
| International Society for Heart Research | Durham | D | $267K |
| Itch Foundation Inc | Durham | F | $0 |
| Jaime Leandro Foundation for | Chapel Hill | B | $4.83M |
| Kaylees Legocy | South Mills | C | $63K |
| Keatons Place | Asheboro | D | $1.23M |
| Koolen-De Vries Syndrome Foundation | Wilmington | C | $381K |
| Kras Cancer Connect Inc | Charlotte | C | $423K |
| Lamin Keitas Hope | Charlotte | C | $4,986 |
| Lifecare Memory Partners Inc | Wilmington | C | $1.20M |
| Little Man Foundation Incorporated | Macon | F | $242 |
| Living With Autism Inc | Raleigh | C | $3.92M |
| Lucans Lions Inc | Matthews | D | $3,260 |
| Lump to Laughter Inc | Writsvlle BCH | C | $83K |
| Lung Cancer Initiative | Raleigh | A | $1.69M |
| Madelyns Fund | Charlotte | C | $963K |
| Makhosi Michaela Foundation | Charlotte | C | $19K |
| Mama Bear Autism Foundation | Moyock | D | $76K |
| Meggs Foundation II Inc | Charlotte | B | $140K |
| Metrolina Association for the Blind Inc | Charlotte | A | $4.58M |
| Miles Against Melanoma NC | Waxhaw | C | $32K |
| Minutes Matter - Mcadd | Wilkesboro | D | $58K |
| Miraclefeet | Chapel Hill | C | $8.72M |
| Monarch Lavender | Asheville | D | $0 |
| Move for Jenn Foundation | Charlotte | C | $220K |
| MPN Cancer Connection | Mint Hill | F | $173K |
| Nash Autism Seeking Hope | Nashville | C | $191K |
| National Association of Family Care Homes | Garner | C | $5,275 |
| National Fabry Disease Foundation | Hillsborough | B | $592K |
| National Kidney Services Inc | Charlotte | A | $173K |
| No Baby Blisters | Winston Salem | C | $7.13M |
| North Carolina AIDS Action Network | Raleigh | C | $265K |
| North Carolina Allergy Asthma & | Raleigh | A | $153K |
| North Carolina Dental Society | Cary | C | $1.05M |
| North Carolina Society of | Charlotte | B | $530K |
| North Carolina Spinal Cord Injury Associ | Cary | C | $108K |
| Oasis NC | Wilmington | B | $644K |
| Olivia S Peters Pediatric | Wilmington | D | $9,957 |
| Oliviastrong Foundation Inc | Matthews | C | $81K |
| Outer Banks Dementia Friendly | Kitty Hawk | C | $136K |
| Piedmont Down Syndrome Support Ne | Winston Salem | C | $264K |
| Pink Ladies of Wilson | Wilson | D | $81K |
| Prayers for Elijah | Concord | B | $3,022 |
| Quest Academics | Charlotte | C | $58K |
| Racing for Als Inc | Apex | C | $506K |
| Raleigh Testicular Cancer | Raleigh | C | $64K |
| Richies Alliance for Autism Inc | Maggie Valley | C | $91K |
| Richmond County Cancer Care Treasure Shop | Rockingham | A | $500K |
| Riders Fighting Breast Cancer Inc | Charlotte | A | $13 |
| Rosani Lens Project | Lake Lure | C | $73K |
| Ryzabove Fitness Company | Charlotte | B | $138K |
| Shallow Ford Foundation Inc | Clemmons | C | $3.48M |
| Sisters Network Triangle | Durham | C | $68K |
| Skraban-Deardorff Syndrome Foundation | Indian Trail | D | $149K |
| Smile Together Corp | Winston Salem | B | $68K |
| Southeast Clinical Oncology | Winston Salem | B | $2.89M |
| Southeastern Fracture Consortium | Chapel Hill | A | $246K |
| Southeastern Kidney Council Inc | Raleigh | C | $0 |
| Southern Society of Urological Surgeons | High Point | A | $86K |
| Spina Bifida of Surry Foundation | Mount Airy | C | $11K |
| Stxbp1 Foundation | Holly Springs | C | $1.42M |
| Teal Diva | Matthews | B | $309K |
| Team Drea Foundation Inc | Raleigh | C | $264K |
| The Alliance of AIDS Services-Carolina | Raleigh | C | $696K |
| The American Board of Anesthesiology Inc | Raleigh | B | $26.63M |
| The Aphasia Recovery Connection Inc | Leland | C | $73K |
| The Barry L Joyce Cancer Support Fund | Madison | D | $1.03M |
| The CCHC Foundation | New Bern | D | $30K |
| The Common Thread for the Cure | Lexington | D | $323K |
| The Four Arrows Foundation Inc | Greensboro | C | $10K |
| The Jiti Foundation | Durham | D | $17K |
| The Joe Martin Als Foundation | Charlotte | C | $666K |
| The Lung Transplant Foundation | Cary | C | $423K |
| The North Carolina Chapter of the | Raleigh | B | $177K |
| The Outlaw Foundation Inc | Newton Grove | C | $143K |
| The Pink Bow Campaign Inc | Charlotte | C | $89K |
| The Rady Lady Foundation Inc | Asheboro | B | $33K |
| The Sisters Inspiring Sisters Inc | Raleigh | A | $62K |
| The Steady Collective Inc | Asheville | C | $355K |
| The Vulver Pain Foundation | Graham | C | $54K |
| The Well Project Inc a Not for Profit Co | Raleigh | C | $1.13M |
| The Wide Open Charitable Foundation | Raleigh | C | $15K |
| Tick-Borne Conditions United Inc | Pittsboro | B | $32K |
| Triad Be Head Strongorg Inc | Greensboro | F | −$785 |
| Vector-Borne Disease Alliance Inc | Chapel Hill | F | $0 |
| Village Heartbeat Inc | Charlotte | C | $1.79M |
| Vision Resource Center | Fayetteville | C | $246K |
| Wards Foundation | Charlotte | D | $955K |
| Western North Carolina Epilepsy Association | Hickory | C | $1,750 |
| Wfu Sigma Chi Derby Days Foundation Inc | Winston Salem | C | $73K |
| Wilderness Road Therapeutic Camping | Cameron | B | $29K |
| Worldclass Foundation | Raleigh | C | $153K |
| Zachs Toy Chest | Holly Springs | C | $128K |
Charity Clarity