| American Pediatric Surgical Nurses | Jefferson Cty | B | $194K |
| Biomed Valley Corporation | Kansas City | D | $14.04M |
| Children's Miracle Network of Greater | Manchester | A | $3.19M |
| Chinese Genomics Meetup Association | Chesterfield | D | $0 |
| Connors Cause | Kirkwood | A | $38K |
| Ethans Rodeo NFP Inc | Palmyra | D | $48K |
| Fleur de Lis | Saint Louis | B | $387K |
| Head for the Cure Foundation | Kansas City | B | $2.49M |
| International Foundation for Autoimmune&Autoinflammatory Arthri | Saint Louis | B | $1.32M |
| International Society for Autism | Kansas City | A | $1.24M |
| International Society for Contact Lens | Saint Louis | C | $303K |
| Jordan Hays Foundation | Wentzville | C | $82K |
| Katie Centorbi Foundation | Lake ST Louis | B | $89K |
| Knockout Ald | Chesterfield | D | $86K |
| Landons League Foundation | Ofallon | D | $9,450 |
| Levelup Kids Inc | Kansas City | A | $3.14M |
| Lizzys Walk of Faith | Columbia | C | $478K |
| Lyle Rakers Charitable Foundation | Cottleville | F | $191K |
| Masons Give a Heart Foundation Inc | Raymore | D | $13K |
| Midwest Health Initiative | Saint Louis | B | $534K |
| Midwest Veterans' Biomedical Research | Kansas City | B | $3.20M |
| National Association of Medical | Savannah | D | $122K |
| Neonatalprogeroidsyndromelimited | Ellisville | C | $85K |
| North American Primary Care Research Group | Kansas City | A | $1.57M |
| Novus Health Inc | Saint Louis | A | $13.03M |
| Paint the Parkway Pink | Saint Joseph | C | $25K |
| Poplar Bluff Heroes Inc | Poplar Bluff | A | $406K |
| ST Louis Integrated Health Network | Saint Louis | A | $8.49M |
| ST Louis Life Sciences Project | Saint Louis | F | $6.06M |
| Starkloff Disability Institute | Saint Louis | C | $3.11M |
| Stowers Institute for Medical Research | Kansas City | C | $102.01M |
| Take Part Inc | Ofallon | C | $267K |
| The Aphasia Network | Kansas City | C | $16K |
| The Cute Syndrome Foundation | Ozark | B | $365K |
| The Matthew and Andrew Akin Foundation | Bridgeton | C | $23K |
| Warrior William Project | Imperial | C | $35K |
Charity Clarity