| A Door of Hope Pregnancy Center | Wilmington | C | $728K |
| Aetna Hose Hook and Ladder Company | Newark | C | $8.20M |
| Affinity Health Alliance Inc | Wilmington | C | $3.70M |
| AIDS Delaware Inc | Wilmington | A | $10.70M |
| Akasha Freedom Rays Care Inc | Newark | C | $18K |
| American Board of Precision Medicine Inc | Wilmington | D | $100 |
| American Legion Ambulance | Smyrna | B | $2.48M |
| American Patient Access Foundation | Dover | F | $30K |
| Bayhealth Cancer Institute | Dover | C | $64K |
| Bayhealth Foundation Corporation | Dover | F | $2.64M |
| Bayhealth Medical Center Inc | Dover | C | $1.26B |
| Beebe Healthcare Inc | Lewes | A | $0 |
| Beebe Medical Center Auxiliary Inc | Lewes | C | $82K |
| Beebe Medical Center Inc | Lewes | B | $672.21M |
| Beebe Medical Foundation | Lewes | D | $11.35M |
| Beebe Physician Network Inc | Lewes | F | $62.13M |
| Buddysplace Inc | Middletown | B | $92K |
| Cancer Support Community Delaware | Wilmington | C | $1.06M |
| Chatham Bay Foundation | Wilmington | F | $0 |
| Children's Dispensary Irrevocable Trust | Wilmington | D | $212K |
| Christiana Care Gene Editing Institute | Wilmington | C | $1.06M |
| Christiana Care Health Initiatives Inc | Wilmington | C | $4.79M |
| Christiana Care Health Services Inc | Wilmington | A | $3.37B |
| Christiana Care Home Health and | Wilmington | B | $43.32M |
| Christiana Care Pennsylvania Inc | Wilmington | A | $328K |
| Christiana Care West Grove Inc | Wilmington | D | $179K |
| Delaware Breast Cancer Coalition | Wilmington | C | $2.59M |
| Delaware Foundation for Medical Services | Middletown | D | $186K |
| Delaware Health Sciences Alliance LLC | Newark | F | $708K |
| Delaware Medical Education Foundation | Middletown | F | $1.05M |
| Delaware Nonprofit Wellness Inc | Wilmington | F | $255K |
| Delaware School Based Health | Newark | C | $1.68M |
| Do Care Doula Foundation Inc | Dover | C | $220K |
| Down Syndrome Association of | Middletown | C | $720K |
| Easter Seals Delaware & Maryland's | New Castle | C | $37.23M |
| Engaged Health Foundation | Lewes | F | $105K |
| Exceptional Care for Children | Newark | A | $19.83M |
| Filipino American Nurse Anesthesiology Society | Dover | F | $182K |
| First State Abortion Fund | Wilmington | D | $260K |
| Five Pointe Professional Liability Insurance Company Co Wilmington Trust | Wilmington | C | $129.41M |
| Foundation for Living Wellness and Health | Claymont | C | $40K |
| Gastro Girl Patient Institute | Dover | D | $1.08M |
| Generations Home Care Inc | Wilmington | C | $3.22M |
| Global Health Support Inc | Wilmington | C | $101K |
| Health Optimization Medicine and Practice Association | Rehoboth BCH | A | $140K |
| Healthcare Leadership Foundation Inc | Dover | C | $61K |
| Hope Wellness Center Inc | Dover | C | $202K |
| Junior Board of Kent General Hospital | Dover | F | $13K |
| K-Day Geriatric Research Center Foundation | Lewes | C | $52K |
| Kent Sussex Dental Society | Dover | A | $15K |
| LA Red Health Center Inc | Georgetown | C | $12.77M |
| Lifeline Beat Foundation | Dover | F | $150K |
| Live Like Lukas Inc | Wilmington | C | $103K |
| Medicine Education and Development for | Dover | A | $4.67M |
| Milton & Hattie Kutz Home Inc | Wilmington | A | $17.56M |
| Nemours New Jersey Physician Practice PC | Wilmington | C | $18.52M |
| Newark Emergency Center Inc | Newark | A | $8.75M |
| Nodehealth Foundation | Lewes | B | $162K |
| One Fact Foundation | Claymont | A | $0 |
| Planned Parenthood Direct Inc | Wilmington | B | $6.85M |
| Planned Parenthood of Delaware Inc | Wilmington | C | $7.19M |
| Preston's March for Energy Inc | Wilmington | F | −$8,608 |
| Public Health Action Network Inc | Dover | C | $107 |
| Red Bird Legacy Foundation | Laurel | D | $44K |
| Southern Delaware Copd Coalition Inc | Millsboro | C | $192K |
| ST Francis Hospital Inc | Wilmington | D | $142.44M |
| Surgical Systems Research Group Inc | Wilmington | C | $70K |
| Sussex Pregnancy Care Center Inc | Georgetown | C | $441K |
| The American Philosophical Association | Newark | C | $1.76M |
| The Andrew Mcdonough B Foundation | Wilmington | C | $10.77M |
| The Delmarva Community Wellnet | Millsboro | D | $117K |
| The Healing Tree SCD Inc | Wilmington | C | $116K |
| The Kendal Corporation | Newark | B | $8.47M |
| The Life Health Center Complex Inc | Wilmington | F | $1.22M |
| The Marino Health Foundation Inc | Wilmington | C | $380K |
| The Rosa Health Center Inc | Lewes | C | $393K |
| Thriving Youth Wellness Inc | Wilmington | C | $163K |
| Tidalhealth Nanticoke Inc | Seaford | C | $245.97M |
| Tidalhealth Physician Network Inc | Seaford | D | $3.60M |
| TSF Incorporated | Wilmington | C | $298K |
| Ubuntu Black Family Wellness Collective | Wilmington | B | $72K |
| Union Hospital of Cecil County Health | Willmington | B | $2.72M |
| Union Hospital of Cecil County Inc | Wilmington | C | $199.13M |
| Union Hospital of Cecil County Oncology Inc | Wilmington | D | $7,030 |
| Village of Hope America Inc | Georgetown | A | $3.98M |
| Wema Healthcare Initiative | Dover | B | $7,500 |
| Wilmington Flower Market Inc | Greenville | C | $116K |
Charity Clarity